Schizophrenia, autism spectrum disorder (ASD), bipolar disorder and attention deficit/hyperactivity disorder (ADHD) are deeply challenging neuropsychiatric conditions1. It disheartens scientists and patients that in vitro assays, genomic analysis, animal models and human brain imaging have yet to deliver definitive insights about them...Research consortia bridge disciplinary divides, and a renewed focus on convergence aims to integrate insight and data from disparate assay modalities.