Key Takeaways: Medicaid unwinding led to significant disruptions in chronic medication therapy for young adults, particularly in states with high enrollment losses. The study utilized a difference-in-differences analysis of the IQVIA Longitudinal Prescription Database to assess prescription continuity. States with higher Medicaid enrollment losses saw greater reductions in active prescriptions and increased cash-pay prescriptions. The findings highlight potential risks of Medicaid funding cuts on chronic disease management for children and young adults.