Monitoring Weight Loss in Pediatric Patients Taking Extended-Release Stimulants for ADHD: In Conversation With Stephen Mateka, DO

 ADHD in the News 2025-07-17


Key Takeaways: The FDA updated labels for extended-release ADHD stimulants, highlighting weight loss risks in children under six due to higher plasma exposure and adverse effects. Clinicians should update informed consent discussions and adjust dosages for young patients, considering the new risk-benefit ratio. Weight monitoring should follow second-generation antipsychotic guidelines, with regular checks and parental input. Alternatives to extended-release stimulants include increased dosing frequency of immediate-release formulations and FDA-approved medications like atomoxetine and guanfacine extended-release.