A recent study published in BMJ Open reports that neurodivergent traits in childhood increase the risk of chronic disabling fatigue (CDF) at 18 years. What is CDF? CDF can accompany various medical conditions, such as myalgic encephalomyelitis (ME/CFS) or long coronavirus disease 2019 (COVID-19). To date, it remains unclear what risk factors may cause certain patients to be more susceptible to the development of chronic fatigue than others.