Although prescription stimulants are often highly effective in reducing ADHD symptoms in children, adolescents, and adults, the misuse (ie, non-medical) of prescription stimulants among adolescents, college students, and adults has become problematic in recent years. Estimates of prescription stimulant misuse vary among studies but meta-analyses report between 5% to 35% of college students in the US report misusing prescription stimulants and varying rates have been reported among military personnel, lawyers, medical, dental, and nursing students