Dopamine neurons’ sensitivity to immune system gene offers clues to hyperactivity and behavioral disorders
Researchers at Duke Health have uncovered a connection between an immune system gene regulator, STAT1, and hyperactive behaviors in mice. Their study, published in the journal Brain, Behavior, and Immunity, demonstrates how prolonged activation of this gene regulator in dopamine neurons disrupts brain function, suggesting a potential link to neurodevelopmental disorders such as autism and ADHD.
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