Young adults and adolescents are the age groups most likely to discontinue ADHD medication within 5 years, according to a new study.¹ Discontinuation of ADHD medication is common. Patients may discontinue their ADHD medication due to unpleasant adverse events like decreased appetite, headaches, sleepiness, irritability, anxiety, insomnia, or mood changes.² About 80% of people who take stimulant ADHD medication experience decreased appetite.³