A transdermal amphetamine therapy was effective at treating pediatric ADHD, according to a phase II trial. In a two-part study, children with attention deficit-hyperactivity disorder (ADHD) using the dextroamphetamine transdermal system (d-ATS) saw a significant improvement in symptoms in a laboratory classroom setting, as measured by the SKAMP (Swanson, Kotkin, Agler, M-Flynn, and Pelham) total score compared with placebo (least-squares mean difference -5.87, 95% CI -6.76 to -4.97, P<0.001), reported Andrew J. Cutler, MD, of SUNY Upstate Medical University in Syracuse in New York, and colleagues.