Human cells in a rat’s brain could shed light on autism and ADHD

Scientists have demonstrated a new way to study conditions like autism spectrum disorder, ADHD, and schizophrenia. The approach involves transplanting a cluster of living human brain cells from a dish in the lab to the brain of a newborn rat, a team from Stanford University reports in the journal Nature.

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ADHD Drugs Negatively Affect Bone Density

A recent study investigated the effect of psychostimulants modafinil, atomoxetine, and guanfacine on the differentiation of mesenchymal stem cells to osteoblasts and on their cell functions, including migration. Researchers determined that the 3 medications commonly used to treat attention-deficit/hyperactivity disorder (ADHD) negatively affect hMSC differentiation to bone-forming osteoblasts and cell migration through different intracellular pathways.(1)

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Annual Stimulant Prescriptions Have Doubled In Adolescents Since 2008

Prescriptions for controlled stimulants among adolescents and young adults have increased significantly in the US since 2008. In a new research letter assessing the recent trends of controlled medication prescriptions for young Americans, a team of Boston investigators observed a substantial increase in stimulants among adolescents aged 13-18 years old and young adults aged 19-25…

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OHSU researchers sharpen estimate of true percentage of people with ADHD

Researchers at Oregon Health & Science University estimate the true percentage of people with Attention-Deficit/Hyperactivity Disorder, or ADHD, in the United States is approximately 3.5% of the population — substantially lower than many common estimates. The study, published this month in the Journal of the American Academy of Child and Adolescent Psychiatry (JAACAP), also found…

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Conditions That Look Like Depression But Aren’t

Mental illness can be difficult to diagnose (via Annals of General Psychiatry). Unlike physical illnesses, such as diabetes and high blood pressure, there are no blood tests or medical instruments to pinpoint many psychiatric disorders. So, it’s important to consult a practitioner who has the right knowledge and expertise.

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Investigators Look at How ADHD, ODD Dimensions Relate to Impulsivity

For the first time ever, investigators have begun to untangle the association between attention deficit/hyperactivity disorder (ADHD) and oppositional defiant disorder (ODD) and the symptoms of impulsivity. A team based in Australia, led by Rapson Gomez, Federation University, evaluated the inter-relationships of dimensions within ADHD and ODD with components of impulsivity.

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Patient Case #1: Co-Managing ADHD

Around the Practice: Management of Adult with Attention Deficit/Hyperactivity Disorder (ADHD) – Episode 10. Drs Stephen Faraone, Theresa Cerulli, Craig Chepke, and Andrew J. Cutler discuss how to co-manage a patient with ADHD with other specialties.

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