Quantifying Genetic Risk in Attention-Deficit/Hyperactivity Disorder

 ADHD in the News 2016-12-15

A pattern of symptomatic persistence in attention-deficit hyperactive disorder (ADHD) beyond childhood and adolescence is strongly associated with a higher genetic risk variant load measured by polygenic risk scores (PRS), researchers reported in JAMA Psychiatry.1 Higher PRS for ADHD, like the presence of greater multimorbidity in some ADHD children, provided markers of greater persistence of ADHD beyond the early childhood years.