Trial quality, bias may diminish value of methylphenidate for ADHD

 ADHD in the News 2016-05-26

A recent clinical review in JAMA reported that evidence supporting the use of methylphenidate among adolescents for treatment of attention-deficit/hyperactivity disorder is of very low quality and should be reconsidered for future therapy guidelines...The researchers conducted a Cochrane review of all randomized controlled trials of methylphenidate, consisting of 38 parallel-group trials and 147 cross-over trials conducted between 1981 and 2014.